Is Zomato accepting online food orders? Is ‘Zomato down today?’ question has taken over the Internet.

Was Zomato down today? Well, DownDetector had confirmed it as user complaints multiplied. While ordering food online, users met with an unusual message on the app which reads, “We’re currently not accepting orders online. We’ll be back soon.” Many users immediately took to Twitter and flooded it with tweets and many even added funny memes. A tweet by Donita Jose asked, “Where you went Zomato.” Surprisingly, and fortunately for all, Zomato was quick to reply to Jose’s tweet and it had some good news.

“Hi Donita, we were facing a temporary glitch. Thanks to our techmates, we are back up and running. We are sorry for any inconvenience caused in the interim and hope to serve you better in the future,” Zomato Care’s tweet reads.

However, the company has not provided any official reason behind the glitch in the services.

What happened to Zomato services 

DownDector chart which shows problem reports submitted in the past 24 hours indicated that around 94 percent of users were facing problems while accessing the Zomato app around 9 PM IST. 6 percent of users were facing the same problem while visiting the Zomato website. 

Downdetector highlights an incident when the number of problem reports is significantly higher than the typical volume for that day.

Meanwhile, Zomato users took to Twitter to express their frustrations with memes. One of the users wrote, “@zomato seems like your servers are not serving you well today.!” While another user humorously said, “Kyu Zomuuu Kyuu? Bhuki marr jau Mai? #ZomatoDown @zomato I’m hungry”

There were some other users who even complained about the cancellation of their orders. 

The only silver lining during the outage was the relative promptness of the Zomato reply and its ability to quickly bring the situation back to normal.

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A new study by researchers at the Marshall University Joan C. Edwards School of Medicine found that lower initial cortisol levels may serve as a predictor for retention in treatment programs for substance use disorder.

The prospective observational study examined the salivary cortisol, stress exposure, adverse childhood experiences (ACEs) and treatment retention of males enrolled in abstinence-based, residential alcohol and drug recovery programs. Their findings were published last month in Alcoholism: Clinical and Experimental Research, the scientific journal on alcohol abuse and treatment for the Research Society on Alcoholism and the International Society for Biomedical Research on Alcoholism.

Cortisol levels reflect a physiological response to stress. In this case, researchers found that participants who remained in the treatment program less than 90 days had significantly higher initial cortisol levels than those who remained in the program longer than 90 days. Further, a Cox proportional hazards model indicated that elevated salivary cortisol, marital/relationship status and ACEs score correlated significantly with hazards of discontinuing the program early.

“Our hope is that these findings will lead to cortisol as a biomarker that can help clinicians determine which individuals might need a more intensive therapeutic approach,” said Todd H. Davies, Ph.D., associate director of research and development at the Joan C. Edwards School of Medicine and corresponding author on the study.

Taylor R. Maddox-Rooper, Kristiana Sklioutouskaya-Lopez, Trenton Sturgill, Caroline Fresch, Charles W. Clements II, M.D.; Rajan Lamichhane, Ph.D.; and Richard Egleton, Ph.D., also served as co-authors on the article. The research team also collaborated with Recovery Point of West Virginia, a long-term, residential recovery program based on the peer-driven model of recovery.

The research team, in collaboration with Recovery Point, currently has a larger follow-up study underway that seeks to identify the clinical significant levels of cortisol. This expanded study also includes a more representative population and examine the hormone oxytocin.

This work is supported by a rural grant from the Marshall University Robert C. Byrd Center for Rural Health through the West Virginia Higher Education Policy Commission. 

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Materials provided by Marshall University Joan C. Edwards School of Medicine. Note: Content may be edited for style and length.

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Orlando (Florida) [US], September 23 (ANI): Developing life-saving drugs can cost billions of dollars and take decades, but researchers have developed a new artificial intelligence-based drug screening technique by using that they hope to shorten the process.

Using a method that models drug and target protein interactions using natural language processing techniques, the researchers achieved up to 97% accuracy in identifying promising drug candidates. The results were published recently in the journal Briefings in Bioinformatics.

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The technique represents drug-protein interactions through words for each protein binding site and uses deep learning to extract the features that govern the complex interactions between the two.

“With AI becoming more available, this has become something that AI can tackle,” says study co-author Ozlem Garibay, an assistant professor in UCF’s Department of Industrial Engineering and Management Systems. “You can try out so many variations of proteins and drug interactions and find out which are more likely to bind or not.”

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The model they’ve developed, known as AttentionSiteDTI, is the first to be interpretable using the language of protein binding sites.

The work is important because it will help drug designers identify critical protein binding sites along with their functional properties, which is key to determining if a drug will be effective.

The researchers made the achievement by devising a self-attention mechanism that makes the model learn which parts of the protein interact with the drug compounds, while achieving state-of-the-art prediction performance.

The mechanism’s self-attention ability works by selectively focusing on the most relevant parts of the protein.

The researchers validated their model using in-lab experiments that measured binding interactions between compounds and proteins and then compared the results with the ones their model computationally predicted. As drugs to treat COVID are still of interest, the experiments also included testing and validating drug compounds that would bind to a spike protein of the SARS-CoV2 virus.

Garibay says the high agreement between the lab results and the computational predictions illustrates the potential of AttentionSiteDTI to pre-screen potentially effective drug compounds and accelerate the exploration of new medicines and the repurposing of existing ones.

“This high impact research was only possible due to interdisciplinary collaboration between materials engineering and AI/ML and Computer Scientists to address COVID related discovery” says Sudipta Seal, study co-author and chair of UCF’s Department of Materials Science and Engineering.

Mehdi Yazdani-Jahromi, a doctoral student in UCF’s College of Engineering and Computer Science and the study’s lead author, says the work is introducing a new direction in drug pre-screening.

“This enables researchers to use AI to identify drugs more accurately to respond quickly to new diseases, Yazdani-Jahromi says. “This method also allows the researchers to identify the best binding site of a virus’s protein to focus on in drug design.”

“The next step of our research is going to be designing novel drugs using the power of AI,” he says. “This naturally can be the next step to be prepared for a pandemic.” (ANI)

(This is an unedited and auto-generated story from Syndicated News feed, LatestLY Staff may not have modified or edited the content body)

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Manchester-based startup Sorted has secured a £3m loan investment to support the growth of its delivery software platform that’s used by the likes of Asda, Lush and ASOS.

Founded in 2010, Sorted’s software is used to analyse the performance of deliveries made by companies, with the goal of optimising the management of both deliveries and returns.

“Customers are now expecting – and demanding – faultless delivery and return experiences as standard, regardless of whether they order from a large multinational brand or a small business,” said Carmen Carey, CEO of Sorted.

“In turn, the next stage in Sorted’s journey is set to provide the SMB market with exceptional delivery and returns capabilities.”

For clients, Sorted provides a centralised hub to manage the delivery aspect of a business, connecting carriers with companies and providing performance insights. For customers of its clients, Sorted provides insights on the tracking of deliveries and manages returns, refunds, and exchanges.

The new investment is the fourth made by Shard Credit Partners’ UK tech venture debt fund. Shard secured the first close of the fund in June, raising £16.5m. The firm is targeting a final close of £75m by the second quarter of 2023.

“Since launching the new venture debt fund in June, our first close investors have continued to enjoy rapid deployment, with a fourth investment now completed,” said Alastair Brown, CEO of Shard Credit Partners.

“Will and his team continue to maintain a robust pipeline of high-quality investments that will ensure the fund remains significantly invested, even as we grow our assets under management with subsequent fund closes through the remainder of 2022.”

Sorted previously raised $40m (£35.3m) in a Series C funding round in December 2021.

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High school students from throughout the Arkansas River Valley will be in Russellville on Thursday, Sept. 22, for an Arkansas Association of Collegiate Registrars and Admissions Officers (ArkACRAO) College Planning Program.

The event will be hosted by the Arkansas Tech University Office of Admissions and will expose high school students to information from universities, colleges, vocational-technical schools and military branches.

The program is planned for 9-11 a.m. at John E. Tucker Coliseum, 1604 Coliseum Drive in Russellville. Parking lot BB will be reserved for guests attending the college planning program.

For more information, call (479) 968-0343.

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Famous for their eight arms, octopuses leverage all of their appendages to move, jet through the water and capture prey. But their movements can look awkward and seemingly unplanned at times, more closely resembling aliens than earthly creatures.

“Normally when you look at an octopus for a short while, nothing is repeatable. They squirm around… and just look weird in their exploratory movements,” said Trevor Wardill, an assistant professor in the College of Biological Sciences who studies octopuses and other cephalopods.

For a new study in Current Biology, Wardill and colleagues investigated whether octopuses preferred certain arms over others when hunting, rather than using each arm equally. A better understanding of how they use their arms will aid efforts to develop next-generation highly manipulative soft robots.

The research team studied the California two-spot octopus, which live for about two years and grow to the size of tennis balls. Octopus arms are numbered on each side of its body, starting at the center. Researchers dropped different types of prey, including crabs and shrimp, into the tanks and recorded video as the octopuses, who were hiding in ornamental SpongeBob “dens” with one eye facing outward, lunged for the snack. Because crabs move slowly while shrimp can flick their tails to escape quickly, each type of prey potentially requires different hunting tactics.

The researchers found:

• Octopuses used arms on the same side as the eye viewing the prey.
• No matter what type of prey came by, each octopus attacked using the second arm from the middle.
• When hunting crabs, octopuses pounced on the prey with a cat-like movement, leading with the second arm.
• When hunting shrimp, the octopuses were more careful to avoid spooking the prey. They led with the second arm and after it made contact with the shrimp, they used neighboring arms one and three to secure it.

Flavie Bidel, the lead author and a postdoctoral researcher in the lab, was shocked at how predictably octopuses began prey capture with the second arm. For creatures whose movement appears unpredictable, the hunting behavior was actually exceedingly repeatable. One of the next steps is to study how neurons facilitate the arm movements.

“Octopuses are extremely strong. For them, to grasp and open a door is trivial, given their dexterity. If we can learn from octopuses, then we can apply that to making an underwater vehicle or soft robot application,” said Wardill. Underwater vehicles inspired by octopuses could play a crucial role in deep ocean exploration.

Funding and support for this work was provided by the Office of Naval Research. The Wardill lab is based in the Ecology, Evolution and Behavior Department in CBS.

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Materials provided by University of Minnesota. Note: Content may be edited for style and length.

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Georgia Tech football dropped an ugly game to Ole Miss on Saturday 42-0. It was one of the worst performances under head coach Geoff Collins and he is sitting squarely on the hot seat. 

One person who seemed aware of this during the game was Ole Miss head coach Lane Kiffin. When talking about if he wanted to get his other quarterback, Luke Altmyer, in the game to throw the ball more, this is what Kiffin had to say: 

“I would have liked the opportunity to throw more with Luke, but having empathy for what was going on in that game on the other sideline and the hot seat or whatever he’s on, just didn’t really feel like it was right, where if it was a couple score game Luke would have gotten to throw more there,”

It is a little strange seeing another head coach talk about another head coach being on the hot seat and saying that he changed his quarterback plan because of it. Kiffin did not need to throw the ball with the way the Rebels were running it as Ole Miss ran for over 300 yards, with Zach Evans and Quinshon Judkins leading the way. 

The loss drops Collins to 10-27 overall as the head coach of Georgia Tech. 

Georgia Tech is back in action on Saturday vs UCF. The game time is 4:00 and the game will be televised on ESPNU. 

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Recruiters from more than 350 companies are headed to Michigan Technological University’s
Career Fair this week — resuming an in-person event that fills local restaurants and
hotels as well as open positions at their companies.

Career Fair runs from 2-7 p.m. on Wednesday, Sept. 21, in Michigan Tech’s Student Development
Complex. Hundreds of follow-up interviews will take place around campus the following
day and virtually afterward. The event is a major factor in Tech’s 93% average job
placement rate within six months of graduation. There are no statistics on how many
meals and memories will be shared, but it’s safe to say that lodging and dining establishments
are rolling out the welcome mat for new and returning visitors.

As of early September, hotels and most other lodging within two hours of the University
were nearly fully booked, said Cody Kangas, executive director of corporate and foundation
relations and acting director of Michigan Tech Career Services. 

Career Services works year-round to help students land co-ops, internships and full-time
jobs, offering programs for both Huskies and companies. Students are offered one-on-one
training in essential skills. Tech’s biannual Career Fair, held in fall and spring,
is where these practice interviews, resume-building sessions and industry outreach
culminate in one of the largest events of its kind in the nation.

It’s been two years since students trekked up MacInnes Drive to the Student Development
Complex, decked out in their business best, to shake hands with their futures. 

“Demand is unprecedented. Employers want to be here — they’re ready to come back,”
said Kangas.

Michigan Tech President Rick Koubek said the response reflects Michigan Tech’s excellence
in building partnerships and preparing students for the job market. 

“A degree from Michigan Tech is highly valued in the marketplace, as evidenced by
the large number of employers attending the University’s Career Fair this year,” he
said. “It’s this level of corporate engagement that helps differentiate the Michigan
Tech student experience. That’s one of the many reasons we are delighted to welcome
employers back to campus this week.”

400+ 

average number of companies recruiting on campus each year

2,000 

recruiters looking to hire Huskies at bi-annual fairs

93% 

average placement rate within six months of graduation

Tech Events Have Regional Impact

The most recent study of Michigan Tech’s impact on the state and regional economy occurred in 2016. It didn’t take visitor spending into account, but a new online visitor data dashboard developed by the Keweenaw Convention and Visitors Bureau (KCVB) does. Brad Barnett,
KCVB executive director, said it’ll be interesting to compare figures for the time
period of the in-person Career Fair to the past two years. Statistics are only available
for the past three years, and are updated about every three months. In the meantime,
he said, the qualitative data is clearly positive.

“We’re excited for the return of Tech’s Career Fair, as it brings in visitors from
across the country seeking to recruit our talented MTU students!”Brad Barnett, executive director, Keweenaw Convention and Visitors Bureau

“Many recruiters are Tech alumni, so Career Fair gives them a chance to return to
Houghton to patronize their favorite local restaurants and reminisce about days on
campus,” said Barnett. “I know the downtown businesses are happy to see the return
of in-person recruiting, along with other University events.”

MTU Huskies Get Ready to Get Hired

For recruiters, it’s a welcome trip to campus. For many students, it’s a new opportunity
to meet employers face-to-face. Most current Huskies have only experienced the virtual
version of Career Fair, a pandemic necessity the past two years. “For the vast majority
of students attending Career Fair this week, it’s the first time they’ve been able
to participate in person,” said Kangas. “The virtual fairs filled a critical need
during what was a very stressful time, but there’s no overstating the importance of
being able to meet potential employers face-to-face. It allows for connections and
conversations that sometimes aren’t possible online.”

Katie Peterson helps students with their resumes during a coaching session at Michigan
Tech Career Services. 

Senior environmental engineering student Katie Peterson has experienced both event formats. Face-to-face wins hands
down. “I went to fall Career Fair when I was a freshman,” she said. “A lot of people
encouraged going, just to see what it was about. I talked to DTE; the recruiter was
really nice. I was invited to a breakfast the next day to find out more about the
company.”

“It’s going to be really exciting to have that in-person experience again.”Katie Peterson ’23, senior environmental engineering student

Making a first impression via video was more difficult, Peterson said. “Having a physical
presence makes a lot of difference.”

Peterson is one of Tech’s career coaches, working with fellow students to help them land co-ops, internships and full-time
jobs. In the days leading up to Career Fair, she and other coaches help students polish
resumes and interview skills. “A little bit of guidance goes a long way,” she said.
“I’m glad we’re here to help.”

Career Fair 2019 included many of the essentials and features Huskies can expect this
year, from connecting to companies they’re most interested in using a mobile app (Career
Fair Plus), to a special appearance by the Huskies Pep Band.

Michigan Technological University is a public research university founded in 1885 in Houghton, Michigan, and is home to more than 7,000 students from 55 countries around the world. Consistently ranked among the best universities in the country for return on investment, Michigan’s flagship technological university offers more than 120 undergraduate and graduate degree programs in science and technology, engineering, computing, forestry, business and economics, health professions, humanities, mathematics, social sciences, and the arts. The rural campus is situated just miles from Lake Superior in Michigan’s Upper Peninsula, offering year-round opportunities for outdoor adventure.

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Black holes are mysterious to start with. No one know what’s inside a black hole because nothing can come out of it once it massive gravitational pull enables it to gobble up things. Not even light can escape from a black hole. And that’s why black hole cannot be ‘seen’ and they can only be detected through the effects it has on surrounding celestial bodies.

Sometimes black holes can ‘sneak around’ though. The supermassive black holes at the centre of galaxies are easily detectable. Others? Not so much.

Scientists have discovered such a sneaky black hole while they were studying system VFTS 243. It is a satellite galaxy in the Tarantula Nebula and it orbits our Milky Way Galaxy. It is 163,000 light-years away from us.

It was suspected till now that all the light reaching us was due to a blue-white star in the system. As scientists studied the star further, they detected that the star had a companion around which it was revolving. But nothing was visible while the gravitational pull on the star was detectable.

The scientists, after more observations and calculations, inferred that there was a black hole around which the star was revolving. The star is maintaining safe distance fron the black hole due to which it is not losing any mass to the black hole.

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An engine made by Jeff Bezos’s Blue Origin LLC appears on track to show it can power heavy payloads to space for the Pentagon after several years of delay, bringing the US closer to ending its politically fraught dependence on a Russian-made model.

An engine made by Jeff Bezos’s Blue Origin LLC appears on track to show it can power heavy payloads to space for the Pentagon after several years of delay, bringing the US closer to ending its politically fraught dependence on a Russian-made model.

Blue Origin predicted in 2014 that its BE-4 engine would be ready by 2017 to launch the new Vulcan rocket built by the United Launch Alliance, a joint venture of top Pentagon contractors Boeing Co. and Lockheed Martin Corp. But the Government Accountability Office as recently as June cited “continued technical challenges in developing a US-produced rocket engine.”

Now, the US Space Force is expressing optimism, saying in a statement that “Vulcan launch system development activities continue to make progress” toward a first test launch by December because “ULA and Blue Origin have completed originally planned BE-4 development testing, and have successfully demonstrated full engine performance.”

United Launch Alliance used the dependable Russian-made RD-180 engine to launch its Atlas V heavy rocket on about 80 successful civil, commercial and national security launches since 2000, according to the Congressional Research Service.

But Congress demanded a replacement for the Russian engines after Russia annexed Crimea in 2014, and that argument has only gained force since President Vladimir Putin’s military invaded Ukraine in February.

Elon Musk, Bezos’s fellow billionaire and competing space entrepreneur, ripped into that Russian connection in his successful fight to compete with what he called the Boeing-Lockheed monopoly for Pentagon satellite launches.

Musk’s Space Exploration Technologies Corp., or SpaceX, has received final certifications to fly its Falcon Heavy rocket to launch the most sensitive classified missions, including the first one between October and December using reusable boosters.

For Bezos, the Space Force’s positive view on his company’s progress provides some good news after closely held Blue Origin was forced to abort a launch Sept. 12 of its suborbital New Shepard rocket shortly after takeoff in West Texas. It was the first major failure for the company since transitioning to routine commercial flights. The New Shepard is powered by an engine different from the BE-4.

United Launch Alliance’s Vulcan program “is now focused on completing BE-4 qualification testing and flight engine deliveries,” the Space Force said in its statement. Its “other elements are progressing through final qualification testing to support initial launch capability.” ULA needs two successful flight tests that are planned for commercial launches as a requirement for Space Force certification that rockets powered by the new engine can carry the most sensitive U.S. military and intelligence cargo.

Frank Calvelli, the Air Force’s assistant secretary for space systems, said in a statement that ULA and Blue Origin “have done a lot to reduce risk, but a lot of work and testing remains to meet this December’s launch.”

The Space Force said it expects to complete ULA’s initial certification of the Vulcan rocket with the BE-4 engine as soon as March 2023 for “lower launch vehicle performance and payload capabilities” and final certification in 2025 for “our largest and most stressing” national security missions.

Those certifications would position ULA to better compete against SpaceX, and possibly other companies, for a third round of as many as 39 national security space launch missions from fiscal 2025 through fiscal 2027, with the first award by October 2024.

“The first BE-4 flight engine is undergoing acceptance testing at Blue Origin’s facilities in Van Horn, Texas,” company spokesman William Boyington said in a statement. “Once final acceptance testing is completed, flight engines will be delivered to ULA, with full-rate BE-4 production already underway.”

Asked about the biggest technical challenges the BE-4 engine has had to overcome, ULA spokeswoman Jessica Rye said in a statement that it’s “the largest liquefied natural gas-fueled engine to be developed, and utilizes a high performance operating cycle. This required the maturation of multiple advanced technologies, which have been proven out through a rigorous development test program.”

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